|
週次 |
日期 |
單元主題 |
|
第1週 |
2/25 |
Master Day |
|
第2週 |
3/03 |
準備週 |
|
第3週 |
3/10 |
臺北醫學大學癌症生物學與藥物研發博士學位學程
蔡淵欽教授
My journey to tumor biology research: Starting from DNA damage responses |
|
第4週 |
3/17 |
吳炫穎
Reversal of phenotypes of cellular senescence by pan-mTOR inhibition. Aging 8(2):1-14, 2016
王証彥
Peripheral Circadian Clocks Mediate Dietary Restriction-Dependent Changes in Lifespan and Fat Metabolism in Drosophila. Cell Metabolism 23(1):143-54, 2016
|
|
第5週 |
3/24 |
陳俊瑋 博士
Senior Research Scientist, Memorial Sloan Kettering Cancer Center, New York, USA
Application of CRISPR technology in cancer research |
|
第6週 |
3/31 |
黃佳華
Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases. Cell 148:421-433, 2012
蔡孟樵
Diluted serum from calorie-restricted animals promotes mitochondrial b-cell adaptations and protect against glucolipotoxicity. FEBS Press doi: 10.1111/febs.13632, 2016 |
|
第7週 |
4/07 |
暫停一次 |
|
第8週 |
4/14 |
王子維
Cancer prevention by adult-onset calorie restriction after infant exposure to ionizing radiation in B6C3F1 male mice. International Journal of Cancer 135, 1038–1047, 2014
吳光凡
Effects of Calorie Restriction and Diet-Induced Obesity on Murine Colon Carcinogenesis, Growth and Inflammatory Factors, and MicroRNA Expression. PLOS One 9, e94765, 2014 |
|
第9週 |
4/21 |
期中考週，暫停一次 |
|
第10週 |
4/28 |
李楨鎬
Subacute calorie restriction and rapamycin discordantly alter mouse liver proteome homeostasis and reverse aging effects. Aging Cell 14(4):547-557, 2015
游適駿
Acetylation of yeast AMPK controls intrinsic aging independently of caloric restriction. Cell 146, 969–979, 2011
|
|
第11週 |
5/05 |
卞毓嘉
Sirtuin 1 promotes the growth and cisplatin resistance of endometrial carcinoma cells: a novel therapeutic target. Lab Invest. 95(12):1363-1373, 2015
王栩沅
Caloric restriction reduces growth of mammary tumors and metastases. Carcinogenesis 32(9):1381-1387, 2011
|
|
第12週 |
5/12 |
林柏亨
Long-lived Indy and calorie restriction interact to extend life span. PNAS 106(23):9262-9267, 2009
林一豪
Caloric restriction modulates Mcl-1 expression and sensitizes lymphomas to BH3 mimetic in mice. Blood. 122(14):2402-2411, 2013 |
|
第13週 |
5/19 |
李盈萱
A role for neuronal cAMP responsive-element binding (CREB)-1 in brain responses to calorie restriction. PNAS 109:621-626, 2011
林彥霐
Caloric restriction induces heat shock response and inhibits B16F10 cell tumorigenesis both in vitro and in vivo. Aging 7(4): 233–239, 2015
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|
第14週 |
5/26 |
鍾建弘
AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD+ elevation. Aging Cell, p1–12, 2016
吳光凡
Muscle-specific 4E-BP1 signaling activation improves metabolic parameters during aging and obesity. J Clin Invest. 125(8):2952-2964, 2015
游適駿
Aging and calorie restriction modulate yeast redox state, oxidized protein removal, and the ubiquitin–proteasome system. Free Radic Biol Med. 51(3):664-670, 2011
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